Drug Target Predictor

Input Compound

COC1CC2CC(CC3CCN(CC4CCCCC4)CC3)C(=O)C2CC1OC	Donepezil
CC12CC3CC(C)(C1)CC(N)(C3)C2	Memantine
NC1C2CCCCC2NC3CCCCC13	Tacrine

Results Description

Pocket ID is a system-defined number of protein binding pocket. RF Prob is probability estimate provied by Random Forest method.
RF Prob > 0.5 generally indicates that the queried compound may bind to the corresponding protein.
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ID	Query	Pocket ID	Protein Name	PDB ID	UniProt ID	RF Prob
1	Donepezil
		P00758	NA	1X8J	Q26490	0.714
		P02198	cmeR	3QQA	Q7B8P6	0.706
		P00229	NA	1GT4	P07435	0.695
		P00561	Ache	2WHP	P21836	0.691
		P00101	PLG	1B2I	P00747	0.686
		P01176	MIF	3IJG	P14174	0.681
		P00472	limA	1NU3	Q9ZAG3	0.68
		P02579	XYLB	4BC5	O75191	0.68
		P01122	TDRD3	2LTO	Q9H7E2	0.678
		P03654	CHKA	5AFV	P35790	0.678
		P00486	Ighv1-72	1OAY	P01751	0.676
		P00517	tag	1P7M	P05100	0.676
		P01373	Endo	2W92	Q93HW0	0.676
		P01929	LPA	3KIV	P08519	0.676
		P02071	PIN1	3I6C	Q13526	0.675
		P00833	chiB1	2A3B	Q873X9	0.674
		P01417	NA	1E6S	P29736	0.674
		P00565	ache	2V96	P04058	0.673
		P01532	SIGLEC5	2ZG1	O15389	0.673
		P02310	NA	4CTJ	A9LIE0	0.673
2	Memantine
		P01176	MIF	3IJG	P14174	0.981
		P02071	PIN1	3I6C	Q13526	0.981
		P01982	TP53BP1	3LGL	Q12888	0.98
		P00101	PLG	1B2I	P00747	0.979
		P02753	susF	4FE9	G8JZS6	0.979
		P00434	GPD	1N1G	P90551	0.975
		P02310	NA	4CTJ	A9LIE0	0.975
		P00477	bla	1NXY	P62593	0.973
		P00787	cobB	4BV2	Q9WYW0	0.973
		P03062	NA	1HYZ	Q76353	0.973
		P00032	fldA	2BMV	O25776	0.972
		P01065	C1QA	2JG8	P02745	0.972
		P01562	chiA	3AS1	Q9AMP1	0.972
		P02516	SMNDC1	4A4F	O75940	0.972
		P03183	FCN2	4NYT	Q15485	0.972
		P01042	PRKAR2A	2IZX	P13861	0.969
		P01327	dscE	2VMC	P42530	0.969
		P03077	PDE10A	4LLP	Q9Y233	0.969
		P03352	CA2	1AVN	P00918	0.969
		P01965	ycgR	3KYF	Q88EQ6	0.968
3	Tacrine
		P00101	PLG	1B2I	P00747	0.908
		P01562	chiA	3AS1	Q9AMP1	0.908
		P01176	MIF	3IJG	P14174	0.907
		P02071	PIN1	3I6C	Q13526	0.907
		P00434	GPD	1N1G	P90551	0.906
		P02753	susF	4FE9	G8JZS6	0.906
		P01982	TP53BP1	3LGL	Q12888	0.902
		P00833	chiB1	2A3B	Q873X9	0.901
		P01065	C1QA	2JG8	P02745	0.901
		P01564	chiA	3ARZ	Q9AMP1	0.901
		P02310	NA	4CTJ	A9LIE0	0.901
		P01327	dscE	2VMC	P42530	0.9
		P03219	GL50803_16453	4OLC	A8BB85	0.9
		P00477	bla	1NXY	P62593	0.899
		P00787	cobB	4BV2	Q9WYW0	0.899
		P01929	LPA	3KIV	P08519	0.899
		P00032	fldA	2BMV	O25776	0.898
		P00249	NCF4	1W70	Q15080	0.898
		P01965	ycgR	3KYF	Q88EQ6	0.896
		P03062	NA	1HYZ	Q76353	0.896