Step 1. Enter your interest compound in the search box

Notice:
Each line contains a compound SMILES and a compound name.
The compound SMILES and the name is separated by a space or a tab.
Please use a combination of numbers, letters, or underscores to name the compound.

The current version can only recognize compounds in SMILES format. For more information about SMILES, please see:
Simplified Molecular Input Line Entry System.

If you do not know the compound's SMILES, You can use Marvin JS for format conversion.

The following steps show a simple example of get compound's SMILES. For more details, see Marvin JS User's Guide.

Step 2. Run Drug Target Predictor and wait for few miniutes

Click "Predict" button to run Drug Target Predictor.

If input correctly, the page will jump to the wait page. In the wait page, you can copy the query ID, the query ID will be used when outputting the result.

If input error, the page will display an error message. You need to check the input compound and resubmit.

Step 3. Get and download your results

The wait page will automatically jump into the result page after some time.

You can also use the query ID to get the results. Paste your query ID to the web link:
http://drug.kiz.ac.cn:8080/targetPre/result/?q=Your query ID
Then paste the link into the address bar of the browser.

In the result page, the topleft box shows the input compound and the topright box shows a brief description of the results and a download link.

The detailed results including the following items:

# ID = ID of queried compounds.

# Query = Name and structure of queried compound.

# Pocket ID = System-defined number of protein binding pocket.

# Protein Name = Unique protein (gene) name in the UniProt (https://www.uniprot.org/).

# Description = Detailed name of the protein.

# Species = The species to which the protein belongs.

# PDB ID = ID of the protein in the PDB (http://www.rcsb.org/).

# UniProt ID = ID of the protein in the UniProt (https://www.uniprot.org/).

# RF Prob = Probability estimation by random forest, the value indicates the possibility of pocket binding, range from 0 (no possibility) to 1 (high possibility).

You can also download the results by click the "Download" link.