Sequence-Based CPI Predictor
Input Compound
Results Description
All predicted results were based on the human proteome sequence. RF Prob is probability estimate provied by Random Forest method.
RF Prob > 0.5 generally indicates that the queried compound may bind to the corresponding protein.
Click to download all analytical results: Download
ID Query UniProt ID Protein Name Description RF Prob
1
Donepezil
P08172 CHRM2 Muscarinic acetylcholine receptor M2 0.878
P11229 CHRM1 Muscarinic acetylcholine receptor M1 0.817
P11940 PABPC1 Polyadenylate-binding protein 1 0.804
P31941 APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 0.793
P09471 GNAO1 Guanine nucleotide-binding protein G(o) subunit alpha 0.792
P56937 HSD17B7 3-keto-steroid reductase 0.766
P48449 LSS Lanosterol synthase 0.763
P20309 CHRM3 Muscarinic acetylcholine receptor M3 0.752
P63096 GNAI1 Guanine nucleotide-binding protein G(i) subunit alpha-1 0.737
Q15125 EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 0.731
P08173 CHRM4 Muscarinic acetylcholine receptor M4 0.729
Q05193 DNM1 Dynamin-1 0.717
P37058 HSD17B3 Testosterone 17-beta-dehydrogenase 3 0.714
P15169 CPN1 Carboxypeptidase N catalytic chain 0.699
Q96IY4 CPB2 Carboxypeptidase B2 0.685
Q6ZMT4 KDM7A Lysine-specific demethylase 7A 0.684
P07099 EPHX1 Epoxide hydrolase 1 0.676
P31213 SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 0.676
Q6QHF9 PAOX Peroxisomal N(1)-acetyl-spermine/spermidine oxidase 0.675
Q9UHC9 NPC1L1 Niemann-Pick C1-like protein 1 0.668
2
Memantine
Q99720 SIGMAR1 Sigma non-opioid intracellular receptor 1 0.959
P24046 GABRR1 Gamma-aminobutyric acid receptor subunit rho-1 0.922
P22748 CA4 Carbonic anhydrase 4 0.9
Q9Y2D0 CA5B Carbonic anhydrase 5B, mitochondrial 0.882
P07451 CA3 Carbonic anhydrase 3 0.882
P43166 CA7 Carbonic anhydrase 7 0.856
P35218 CA5A Carbonic anhydrase 5A, mitochondrial 0.846
Q07075 ENPEP Glutamyl aminopeptidase 0.825
P16662 UGT2B7 UDP-glucuronosyltransferase 2B7 0.809
O75762 TRPA1 Transient receptor potential cation channel subfamily A member 1 0.805
Q9ULX7 CA14 Carbonic anhydrase 14 0.803
P09471 GNAO1 Guanine nucleotide-binding protein G(o) subunit alpha 0.801
Q9NYA1 SPHK1 Sphingosine kinase 1 0.78
P07099 EPHX1 Epoxide hydrolase 1 0.778
Q16790 CA9 Carbonic anhydrase 9 0.773
Q96FL8 SLC47A1 Multidrug and toxin extrusion protein 1 0.773
Q9Y4P1 ATG4B Cysteine protease ATG4B 0.768
P07327 ADH1A Alcohol dehydrogenase 1A 0.762
P00325 ADH1B Alcohol dehydrogenase 1B 0.762
P35228 NOS2 Nitric oxide synthase, inducible 0.76
3
Tacrine
P36544 CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 0.949
Q05193 DNM1 Dynamin-1 0.941
P08912 CHRM5 Muscarinic acetylcholine receptor M5 0.938
P09471 GNAO1 Guanine nucleotide-binding protein G(o) subunit alpha 0.917
P11229 CHRM1 Muscarinic acetylcholine receptor M1 0.912
P08173 CHRM4 Muscarinic acetylcholine receptor M4 0.908
P08172 CHRM2 Muscarinic acetylcholine receptor M2 0.903
Q15125 EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 0.899
P48449 LSS Lanosterol synthase 0.883
Q99720 SIGMAR1 Sigma non-opioid intracellular receptor 1 0.874
P31941 APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 0.869
P18089 ADRA2B Alpha-2B adrenergic receptor 0.853
P11940 PABPC1 Polyadenylate-binding protein 1 0.845
Q9Y5N1 HRH3 Histamine H3 receptor 0.836
O15245 SLC22A1 Solute carrier family 22 member 1 0.817
Q9HC16 APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 0.806
P20309 CHRM3 Muscarinic acetylcholine receptor M3 0.789
P18825 ADRA2C Alpha-2C adrenergic receptor 0.787
P07327 ADH1A Alcohol dehydrogenase 1A 0.775
P63096 GNAI1 Guanine nucleotide-binding protein G(i) subunit alpha-1 0.771
Sequence-Based CPI Predictor